
Nisibis’s reputation was founded not only on the monasteries of the Izla mountains, however, but also on the School of Nisibis, which was likewise traced back to Bishop Jacob, who wanted to fight Arianism, which had been condemned at the Council of Nicea in 325. In any case, we know that he employed Ephrem the Syrian as a biblical exegete. When the city was handed over to the Sassanian king Shapur II in 363, Christian instruction ceased, and Ephrem fled to Roman Edessa, where he taught until his death and supported his bishop in the fight against Arianism.
Baumer, The Church of the East, p. 22
Ancient Nisibis is modern Nusaybin, Turkey. And Edessa is now called Sanliurfa. I’ve often heard of the battles over Arianism that took place in major cities like Alexandria, Egypt. Fascinating then to hear what was also happening in these eastern border cities often fought over by the Romans and the Persians.
Photo by Wikimedia Commons.